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OX401 is the second candidate utilizing Onxeo's proprietary platform of decoy agonists, platON™. OX401 was designed by capitalizing on Onxeo’s expertise of oligonucleotides acting as decoy agonists and exhibits very original properties.

Onxeo is the French orphan-drug specialist in Oncology who has various pipelines for certain cancers.… By Dani Stock analysis for Onxeo SA (ONXEO) including stock price, stock chart, company news, key statistics, fundamentals and company profile. Onxeo S.A. recently announced positive preclinical proof-of-concept results Onxeo's comprehensive portfolio features a broad orphan oncology pipeline, with 10 Mar 2021 Onxeo S.A. (Euronext Growth Paris: ALONX, First North generates new innovative compounds and broaden the Company's product pipeline. Paris (France), Copenhagen (Denmark) – Onxeo S.A. (Euronext Paris, Nasdaq Through compelling technologies and a strong product pipeline targeting 7 Jan 2021 Onxeo S.A. (Euronext Paris, NASDAQ Copenhagen: ONXEO), new innovative compounds and broaden the Company's product pipeline. 29 Feb 2016 Deal will give Onxeo a signal-interfering DNA (siDNA) molecule it says has Onxeo added that even with Dbait/DT01 joining its pipeline the کپی پیوند به توییت; قراردادن توییت در سایت خود. $ONXEO pipeline & milestones (october)pic.twitter.com/gT7FsGmY9G. ۱۰:۰۳ - ۱۷ مهر ۱۳۹۷.

Onxeo pipeline

Onxeo. Onxeo designs and develops novel oncology drugs targeting tumor DNA repair functions.

CAD. NORDEN: BANKERNA STARKA, BIOTEKNIKFLOPP FÖR ONXEO, VINX30 +0,8% Med ett flertal miljardaffärer i pipeline ser vi goda förutsättningar för att Specific DRP®'s are developed for each pipeline product, which will enable In-licensing agreement with Onxeo A/S for the drug candidate om Deadlinen på Kina-aftalen; han sagde at den var intakt. 150 er konservativt med deres spændende pipeline. Vis mere.

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20-45%. Original belåningsgrad %. 20%. PANDORA A/S INTER PIPELINE LTD. Valuta. CAD. NORDEN: BANKERNA STARKA, BIOTEKNIKFLOPP FÖR ONXEO, VINX30 +0,8% Med ett flertal miljardaffärer i pipeline ser vi goda förutsättningar för att Specific DRP®'s are developed for each pipeline product, which will enable In-licensing agreement with Onxeo A/S for the drug candidate om Deadlinen på Kina-aftalen; han sagde at den var intakt.

Belåningsgrad. 20-45%. Ordinær belåningsgrad.
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platON™ is Onxeo’s proprietary chemistry platform of oligonucleotides acting as decoy agonists, which generates new innovative compounds that broaden the Company’s product pipeline. AsiDNA™, the first compound sourced from platON™, is a first-in-class, highly differentiated DNA Damage Response (DDR) inhibitor based on a decoy mechanism Onxeo Expands its Pipeline with New Optimized Lead OX401 Entering Proof-of-Concept Preclinical Phase. OX401 is the second candidate utilizing Onxeo's proprietary platform of decoy agonists, platON™. OX401 is optimized to be a next-generation PARP inhibitor, designed to act on both the DNA Damage Response and the activation of immune response.
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Onxeo is a French clinical-stage biotechnology company designing and developing novel oncology drugs targeting tumor DNA-binding functions. Our therapeutic strategy focuses on fighting tumor resistance to treatments which poses ever-greater therapeutic challenges, further more so in aggressive or rare cancers.

Onxeo S.A. | 5 051 följare på LinkedIn. Onxeo is a clinical-stage biotechnology company developing novel oncology drugs targeting tumor DNA-binding functions.

Onxeo is developing innovative oncology drugs based on DNA-targeting and epigenetics. The lead compound, AsiDNA, is a first-in-class DNA break repair inhibitor based on a unique decoy mechanism and currently evaluated in a phase I trial (DRIIV-1) for systemic administration in solid tumors.

Onxeo’s R&D pipeline also includes belinostat, an HDAC inhibitor (epigenetics), of which an oral form could be used in combination with other anti-cancer agents for liquid or solid tumors. Belinostat is already conditionally FDA-approved in the US as a 2nd line treatment for patients with peripheral T cell lymphoma and marketed in the US by Onxeo is focused on the development of the next generation of DNA damage repair inhibitors from its novel oligonucleotide platON platform. The lead asset, AsiDNA, belongs to the same class of drugs as PARP inhibitors, but has a different mechanism of action. AsiDNA is in a Phase Ib trial in combination with chemotherapy in solid tumours; preliminary results are expected by end-2019, which is Onxeo has a proprietary platON platform based on a unique decoy technology in the field of DNA damage repair inhibition. The lead asset AsiDNA is in a Phase Ib triple combination trial with chemotherapy in solid tumours and a second Phase Ib/II trial that aims to demonstrate AsiDNA’s potential to abrogate tumour resistance to PARP inhibitors.

Onxeo is also developing AsiDNA™, a first-in-class DNA break repair inhibitor based on a unique decoy mechanism. Onxeo.